Proton pump inhibitors and gastric acid secretion

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Proton Pump Inhibitors and Gastric Acid Secretion

1. Bronowicki JP, Venard V, Botte C, et al. Patient-to-patient transmission of hepatitis C virus during colonoscopy. N Engl J Med 1997;337:237–40. 2. Tytgat GNJ. Endscopic transmission of Helicobacter pylori. Aliment Pharmacol Ther 1995;9(suppl 2):105–10. 3. Yang R, Ng S, Nichol M, et al. A cost and performance evaluation of disposable and reusable biopsy forceps in GI endoscopy. Gastrointest E...

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Predicting Efficacy of Proton Pump Inhibitors in Regulating Gastric Acid Secretion

Developing drugs to treat gastric acid related illnesses such as ulcers and acid reflux disease is the leading focus of pharmaceutical companies. In fact, expenditure for treating these disorders is highest among all illnesses in the US. Over the last few decades, a class of drugs known as a proton pump inhibitors (PPIs) appeared on the market and are highly effective at abating gastric illness...

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Potential uses of intravenous proton pump inhibitors to control gastric acid secretion.

Proton pump inhibitors are the most effective agents for suppressing gastric acidity and are the preferred therapy for many acid-related conditions. While proton pump inhibitors have been accessible in intravenous formulations in several European countries, they have been available only as oral drugs in the United States. In the near future, the proton pump inhibitor pantoprazole is likely to b...

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Proton Pump Inhibitors Inhibit Pancreatic Secretion: Role of Gastric and Non-Gastric H+/K+-ATPases

The mechanism by which pancreas secretes high HCO3- has not been fully resolved. This alkaline secretion, formed in pancreatic ducts, can be achieved by transporting HCO3- from serosa to mucosa or by moving H+ in the opposite direction. The aim of the present study was to determine whether H+/K+-ATPases are expressed and functional in human pancreatic ducts and whether proton pump inhibitors (P...

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Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors

Äbelö, A. 2003. Pharmacodynamic Modelling of Irreversible and Reversible Gastric Proton Pump Inhibitors. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy 303. 47 pp. Uppsala. ISBN 91-554-5806-8. Acid related diseases like GERD, duodenal-and gastric ulcers and H. Pylori-positive peptic ulcer disease are primarily managed by reducing ga...

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ژورنال

عنوان ژورنال: The American Journal of Gastroenterology

سال: 2001

ISSN: 0002-9270,1572-0241

DOI: 10.1111/j.1572-0241.2001.05362.x